Core Labs
For animal models click "Animal Models at UofL" subtab above.
CTR Imaging Suite - New Core for Researcher use.
The Department of Radiology announces the OPENING of "CTR Imaging Suite" in the Vivarium of the
Clinical Translational Research Building at 505 S. Hancock St., Room 14. The CTR Imaging Suite houses the following sets of instrumentation for researchers working with animals to image their science.
1. Siemens R4 Micro-PET (Knoxville, TN)
2. Siemens MicroCAT II (formerly ImTek, Inc./ Knoxville, TN)
3. Agilent Technologies 9.4T, 31-cm Bore MRI/MRS (formerly Varian, Inc., Santa Clara, CA)
4. Maestro In Vivo Fluorescence Imaging System (formerly CRI, now Caliper LS, Hopkinton, MA)
5. Biospace Lab Photon Imager (rue Mercoeur, Paris)
6. VisEn FMT 2500 LX (PerkinElmer, Waltham, MA)
For more information, please contact Chin K. Ng, Ph.D. at 852-5875.
Click title of core below for more information.
Analytical Microscopy Laboratory
Director: Ferrell R. Campbell, Ph.D.
The Core has a confocal and a Nikon TiE fluorescent microscope.
Biomolecular Mass Spectrometry Core Laboratory (Web link is currenlty under construction)
Director: William M. Pierce, Ph.D.
This core laboratory has a focus on application of mass spectrometry techniques in biomedical research. This includes studies of protein structure and function, proteomics, altered nucleic acid structure and xenobiotic metabolism.
Fresh Human Tissue Laboratory
Director: Stephanie Dearing, Assistant Director
The core provides cadaver tissue and bodies for clinical research, including surgical techniques, isolation of cells and specific tissue.
KBRIN Bioinformatics Core
Directors: 1) Eric C. Rouchka, D.Sc. 2)Ted Kalbfleisch, Ph.D.
1) In addition to supporting statewide initiatives such as a regional bioinformatics summit, the UL core supports a colloborative bioinformatics research project with the aim to analyze genomic, proteomic and metabonomic factors which contribute to breast cancer. 2) A community based participatory research core will work with community health centers to develop databases for de-identified electronic medical records for research purposes.
Microarray - DNA Sequencing Core - James Graham Brown Cancer Center
Director: Wolfgang Zacharias, Ph.D.
Specific Aims: 1. Provide services for microarray-based gene expression and genotyping analysis; 2. Educate and train users in strengths and limitations of microarray technology; 3. Assist in experimental design, sample processing, and data analysis; 4. Maintain close interactions with other UofL Cores to support customer needs in basic and clinical translational research; 5. Provide logistic support for projects, grants, and manuscripts.
Nucleic Acid Core - CGeMM Core
Director: Ronald Gregg, Ph.D.
This core provides DNA sequencing, genotyping , real-time PCR and robotic liquid handling to U of L investoigators. Major equipment items include: ABI 3130XL DNA sequencer, Biomek 2000 liquid handling system, MJ Research Quad thermal cycler.
Proteomics Laboratory - CEGIB Core
Director: Jon Klein, M.D., Ph.D.
This core laboratory has a focus on application of mass spectrometry techniques to clinical problems in disease biomarker identification and discovery of pathophysiologic mechanisms.
Integrative Health Sciences Facility Core (IHSFC) - CEGIB Core
Co-Directors: David Tollerud, M.D., Ph.D. and Roland Valdes, Jr., Ph.D.
The central goal of the IHSFC is to provide investigators in CEGIB with services and consultation that facilitate translation of basic research findings into clinical or public health applications.
Brown Cancer Center Shared Cores
Director: Donald M. Miller, M.D., Ph.D.
Price Institute of Surgical Research
Director: Susan Galandiuk, M.D.
ArcturusXT microdissection system
Institute strives to enhance the care of patients through advances in surgical techniques and technology and through basic and clinical research.
Center for Regulatory and Environmental Analytical Metabolomics - CREAM
Director: Teresa Fan, Ph.D.
This program will develop cutting-edge methodologies and approaches for the emerging metabolomic and system biochemical research and has the promise of revolutionizing biological research in the 21st century for the ability to resolve biological complexity.
