March 24: Practical Workshop Belknap Research Building, U of Louisville

8:30 am  Session I

• Dr. Andrew Lane, Brown Cancer Center, University of Louisville

Title:  "Positional Isotopomer analysis by NMR for Metabolic Pathway Tracing"

 9:30 am  Session II

• Dr. Richard Higashi, Department of Chemistry, University of Louisville

• Dr. Erik Larson, National Food Institute, Technical University of Denmark, Copenhagen

Title:  "HPLC or GC coupled with ICP-MS for Targeted Metallo-metabolite Analysis"

• Dr. Jack Henion, Advion BioSciences

Title:  "Chip-Based Nano Electrospray Mass Spectrometry: Background and Applications for Studies in the Life Sciences."

• Dr. Mark Libardoni, LECO Corporation

• Dr. Anne Ferguson, Thermo Fisher Scientific

Title:  "An Integrated Approach to Metabolomics"

12:30 pm  Lunch and Demonstrations

3:30 pm  Session III

• Dr. Masanori Arita, Dept. of Computational Biology, University of Tokyo

Title:  "Database for Flavonoids and Measurement in Arabidopsis"

• Dr. Maciek R. Antoniewicz, Department of Chemical Engineering, MIT

Title:  "Elementary Metabolite Unites (EMU): A Novel Framework for Modeling Isotopic Tracer Distributions and Determining Metabolic Fluxes"

March 25: Frontiers in Isotopomer Metabolomics, Brown Hotel

8:15 am  Session I: Clinical Applications. Chair, Dr. Teresa Fan

• Dr. Donald Miller, JG Brown Cancer Center, University of Louisville

Title:  "In Vivo Mteabolomic Analysis of Human Lung Cancer."

• Dr. Graeme Mason, Psychiatry and Diagnostic Radiology, Yale Magnetic Resonance Research Center, Yale University, School of Medicine

Tilte:  "Evaluations of Metabolic Pathways with ¹³C Detection"

• Dr. Rima Kaddurah Daouk, Dept. of Psychiatry and Behavioral Sciences, Duke University Medical Center

10:45 am  Session II: Metabolomics meets other -omics. Chair, Dr. William Pierce

• Dr. Dan Liebler, Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt University

Title:  "Metabolomics meets Proteomics: Protein Targets of Reactive Lipid Oxidaton Products in Oxidative Stress."

• Dr. Lloyd Sumner, The Samuel Robers Noble Foundation

Tilte:  "Integrated Functional Genomic Studies of the Model Legume Medicago truncatula."

1:30 pm  Session III: Agency Perspective. Chair, Dr. Rima Kaddurah Daouk

• Dr. David Balshaw, Program Director, NIEHS

Title:  "Approaches to Addressing Long Standing Issues in the Environmental Health Sciences."

2:15 pm  Session IV: Flux Modeling. Chair, Dr. Joanne Kelleher

• Dr. Joanne Kelleher, Department of Chemical Engineering, MIT

Title:  "Analyusis of Metabolite Labeling using Stable Isotope Tracers Reveals Distinctive Pathway of Glutamine Metabolism in Transformed Cells."

• Dr. Marta Cascante, Biochemoinformatics, University of Barcelona

Title:  "From the Analysis of Cell Metabolic Adaptation to Rational Drug Development."