Outreach and Broader Impact
High School Students
High school and Junior High school students sponsored and mentored by the University of Louisville faculty listed to work on the projects of the Metabolomics Initiative. All authored and presented posters at various regional events like the Regional Science Fair, Dupont Manual High School.
High School students in Dr. Yappert's lab.
Many University of Louisville undergraduate students, and some from other institutions within Kentuckiana, receive hands-on instruction at CREAM. Undergraduate students participate in all aspects of research including conducting their own projects, developing analytical methods, and preparing platform and poster presentations.
Undergraduate Student Kathleen Marshall in Dr. Fan's lab.
- Sandra Gomes - Sao Paulo. Sample preparation for SIRM studies of glutaminase C in cancer cells.
- Scott Jones – Medicine at University of Louisville. Natural products involved in pre-Parkinson’s disease symptoms.
- Anne Le - Johns Hopkins University. SIRM analysis of MYC expression in cancer cells.
- Santigo Moralli – University of Barcelona. High-throughput metabolite analysis, specifically the study of the lipidome and its changes during cell cycle progression and tumor transformation.
- Jason Podrabsky - Oregon State. GC-MS analysis of killifish embryos.
- Miriam Porquet – University of Barcelona. Study of metabolic and lipid profiles of mouse embryogenic fibroblast cell lines using LTQ FT MS and GCMS techniques and software to describe the metabolic importance of the lack of two key enzymes (CDK4 and CDK6) in the cell cycle.
- Chris Ricketts and Youfeng Yang - NCI SIRM studies of metabolic reprogramming in fumarate hydrate null cells
- Pankaj Seth - Beth Israel Deaconess, Boston. SIRM analysis of LDH-A knockdowns in cancer cells.
- Mariia Yuneva – University of California, San Francisco. Molecular regulatory mechanisms of Myc oncogene in mammalian cells.
Bringing the most current and innovative work in the Metabolomics discipline to students and scientists in the Louisville area is an important mission of the Center. Three Metabolomics symposia have been hosted by the Center:
Group photo for the 2007 Metabolomics Symposium.
Introducing Metabolomics to a diverse community
- September 15, 2007 - Kentucky Association for Environmental Education: Metabolomics in bioavailability, mechanism, and biomarker discovery
- November 2, 2007 - Kentucky Science Teachers Association: Metabolomics and Isotopomer analysis
- November 21, 2009 - JG Brown Cancer Center and Marky Cancer Center Colloquium, CTRB Louisville: “Translating Metabolomics into Novel Cancer Therapeutics“.
- Fall 2010 - Berea College: Dr. Teresa Fan presenting "Metabolism: Old or Gold?".
- Fall 2010 - Huntingdon College: Dr. Hunter Moseley presenting "Metabolic Modeling of Converging Metabolic Pathways. Analysis of Non-Steady State Stable Isotope-Resolved Metabolomics of UDP-GlcNAc and UDP-GalNAc."
- August 2011 - Summer Student Program, JG Brown Cancer Center: “Clinical Applications of Stable Isotope-Resolved Metabolomics (SIRM) in Non Small Cell Lung Cancer”.