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About Us
The Medicinal Chemistry Core provides medicinal and organic chemistry support for drug discovery, specializing in lead optimization and synthesis of compound libraries.
The Medicinal Chemistry Core is a core component of the Drug Discovery Platform.
Services
- Design and synthesis of compound libraries (Lead Optimization)
- Scale up of compounds (1 - 5 g)
- Design and synthesis of probes (fluorescent and isotopic)
- Custom synthesis
- Thermodynamic solubility
- Solution stability
- Quality assurance (purity determination)
- Consultation
Serving
- UofL Researchers
- External-Academic
- External-Industry
Core Acknowledgement
Researchers are strongly encouraged to acknowledge the use of this core facility in publications and presentations. Doing so documents the role of shared infrastructure in advancing UofL research and supports the core’s continued operation and growth.
Consider using the suggested language below when making acknowledgements in your work:
This [publication, project, or research] was made possible, in part, by the Medicinal Chemistry Core [RRID:SCR_026397] at the University of Louisville.
Core Personnel
Joseph Burlison
Director, Medicinal Chemistry Core