Proteomics Technology Center
Actively pursuing Louisville Research Core designation
Sidebar
About Us
The Proteomics Technology Center (PTC) provides comprehensive proteomic analyses using LC-MS platforms, supporting post-translational modifications, protein-protein interactions, spatial proteomics, and single-cell workflows with bioinformatics.
Services
- Data-dependent acquisition (DDA) LC–MS/MS with advanced database searching (Proteome Discoverer, SequestHT, MASCOT)
- Data-independent acquisition (DIA) LC–MS/MS for quantitative proteomics (Spectronaut, PEAKS)
- Label-free and quantitative proteomics workflows
- De novo peptide sequencing and post-translational modification (PTM) analysis (PEAKS PTM, Scaffold PTM, Maxquant)
- Protein–protein interaction (PPI) analysis using chemical crosslinking and MS (PD-XLINKX)
- High-resolution LC–MS platforms, including Orbitrap and Q-Exactive systems
- FAIMS-enabled proteomic separations for enhanced depth and selectivity
- Bioinformatics and statistical analysis of proteomics datasets
- Method development and experimental design consultation
Serving
- UofL Researchers
- External-Academic
- External-Industry
Core Acknowledgement
Researchers are strongly encouraged to acknowledge the use of this core facility in publications and presentations. Doing so documents the role of shared infrastructure in advancing UofL research and supports the core’s continued operation and growth.
Consider using the suggested language below when making acknowledgements in your work:
This [publication, project, or research] was made possible, in part, by the Proteomics Technology Center [RRID:SCR_027969] at the University of Louisville.
Core Personnel
Michael L. Merchant
Professor of Medicine, Director PTC
Timothy D. Cummins
Associate Professor of Medicine, Associate Director PTC