Bioimaging Core
Actively pursuing Louisville Research Core designation
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About Us
The Bioimaging Core provides biological electron microscopy services including sample preparation, SEM and TEM imaging, array tomography, and cryo-EM plunge freezing.
The Bioimaging Core is a core component of the Micro/Nano Technology Center (MNTC).
Services
- Biological Sample Resin Embedding
- Biological Sample Dropcasting
- rOTO Enhanced Contrast Sample Preparation
- Cryo EM Plunge Freezing
- Critical Point Drying
- Sputter Coating
- Vacuum Curing
- Ultramicrotomy
- Scanning Electron Microscopy
- Transmission Electron Microscopy
Equipment & Instruments
- Tousimi Critical Point Dryer
- Ted Pella Sputter Coater
- Blue M Vacuum Curing Oven
- Leica EM Tissue Processor
- Leica EM UC7 Ultramicrotmome
- Leica UCT Ultracut Ultramicrotome
- ThermoFisher Scientific Apreo SEM ThermoFisher Scientific Apreo SEM SOP
- Hitachi-7700 TEM Hitachi-770 TEM SOP
- Leica GP2 Plunge Freezer
Bioimaging Core Facility Rates
| Equipment/Process | Internal | External-Academic | External-Industry |
|---|---|---|---|
| Labor/hour | $72.00 | $101.00 | $115.00 |
| Ultramicrotome/min | $0.82 | $1.15 | $1.30 |
| Hitachi HT-7700 TEM/min | $1.23 | $1.73 | $1.97 |
| 3i Light Sheet Microscope/min* | TBD | TBD | TBD |
| Light Sheet Data Analysis Work Station/min | TBD | TBD | TBD |
*The 3i Light Sheet Microscope is coming online in the Fall of 2026
| Batch Processes/Consumables | Internal | External-Academic | External-Industry |
|---|---|---|---|
| Tissue Processor + Consumables** | $125.00 | $160.89 | $171.74 |
| Glutaraldehyde | $7.00 | $9.01 | $9.62 |
| Osmium Tetroxide | $7.00 | $9.01 | $9.62 |
| Paraformaldehyde | $6.00 | $7.72 | $8.24 |
| Lead Citrate | $25.00 | $32.18 | $34.35 |
| TEM Grid | $3.00 | $3.86 | $4.12 |
| Grid Box | $7.00 | $9.01 | $9.62 |
| Forceps | $45.00 | $57.92 | $61.83 |
**Tissue processor can process up to 54 samples per batch. Does not include labor to prepare reagents.
Serving
- UofL Researchers
- External-Academic
- External-Industry
Core Acknowledgement
Researchers are strongly encouraged to acknowledge the use of this core facility in publications and presentations. Doing so documents the role of shared infrastructure in advancing UofL research and supports the core’s continued operation and growth.
Consider using the suggested language below when making acknowledgements in your work:
This [publication, project, or research] was made possible, in part, by the Micro/Nano Technology Center Bioimaging Core [RRID: SCR_028479] at the University of Louisville and KY INBRE (P20GM103436).
Core Personnel
Sung Jin Kim
Director, MNTC
View research profile
Julia Aebersold
Bioimaging Core Facility Manager
Ana Sanchez Galiano
Associate Director